Effectiveness of Mobile Application–Based Intervention on Medication Adherence Among Pulmonary Tuberculosis Patients A Systematic Review

To analyze the effectiveness of mobile application–based interventions on medication adherence among pulmonary tuberculosis patients. Intervention articles involving patients with pulmonary tuberculosis and/or their families, utilizing mobile application–based intervention research designs, assessing patients individually or in groups with or without a control group, using mobile application–based interventions that can be accessed via a browser, utilizing adherence to treatment as the primary outcome, and written in English and Indonesian were included. The articles published from 2012 to 2022 were obtained from EBSCO Host, ProQuest, GARUDA, PubMed, Scopus, and Cochrane Online Library databases. The Critical Assessment Standards Program was used to assess the trustworthiness, relevance, and results of the published articles. The quality of the articles was assessed according to Johns Hopkins Nursing Evidence-Based Practice guidelines. Seven studies reported that mobile application–based interventions can improve medication adherence, including treatment success, number of missed drugs, correct intake of medications, adherence to health programs, timeliness, and frequency of clinic visits. This review only analyzed the impact of mobile application–based interventions on patients, and their effects on the family, social, and health services were not covered.